The phrase "a problematic long" is not correct and does not convey a clear meaning in written English.
It may be intended to describe something that is both problematic and lengthy, but the construction is awkward and unclear.
Example: "The report was a problematic long, filled with errors and inconsistencies that made it difficult to understand."
Alternatives: "a lengthy issue" or "a troublesome length".
Nevertheless, they were expensive and time-consuming [ 4], often targeting a highly motivated selected group [ 5], manifesting high dropout rates and a problematic long-term adherence [ 6].
This high evolutionary rate seems to be a genome-wide characteristic in Oikopleura dioica and leads to problematic long branches in inferred molecular phylogenies [ 6].
For example, split decomposition [ 32] with spectral analysis [ 33] has been utilized to plot split graphs to show where conflicting signal exists in a molecular data set [ 10, 34- 38], and Relative Apparent Synapomorphy Analysis (RASA [ 39, 40]) has been developed to detect problematic long branches by examining the taxon-variance plot of a molecular data set [ 41- 49].
They could however, be problematic long term, but overcome by the development of an inhaled form of cysteamine for chronic dosing.
The author details how the Russian encounter with Islam was close and problematic long before the twenty-first century and how Russia has recently chosen to interfere in Muslim states of the Middle East, building alliances and making enemies.
Sanders is not where his supporters suppose on the problematic long war and troublesome military spending.
The taxon-variance plot has attracted some zealous criticism in several studies that report false outcomes for identifying problematic long branches [ 50- 54].
It starts a serious conversation about the proper policy responses to problematic long-term economic trends.
The outcome was deemed successful by remission of infection in 16 (80%) of these problematic long-term treated patients.
However, unsatisfactory responses in advanced disease stages, resistance, and problematic long-term tolerability of all three Bcr-Abl inhibitors remain major clinical problems (Jabbour et al., 2010).
We interviewed patients and GPs about their experiences, beliefs and expectations of analgesia prescribing, to improve understanding of how problematic long-term opioid prescribing becomes established.
