It is a particularly problematic disease in chickens (due to their intense rearing conditions), costing the industry £38 million per year in the UK alone and, extrapolating from this, over 2 billion US dollars to the world's farmers and poultry industries annually [1].
HAT caused by Trypanosoma brucei gambiense is a particularly problematic disease and starts to surge during conflict in endemic areas.
Clostridium difficile is a Gram-positive, spore-forming bacterium responsible for C. difficile infection (CDI) in humans [ 1], a serious and increasingly problematic disease.
As our heuristics are still evolving, problematic disease names (e.g. 'Interferon' or 'memory') are entered into a 'cheat list' and removed from the system, with suggestions for improvements ticketed in our Bugzilla databases (http://www.bugzilla.org/), to be addressed in future releases.
Bgl is a causal agent of bacterial grain rot, one of the most problematic diseases of rice [20].
It also argues that new drugs that attack especially problematic diseases should get extra patent protection.A tragedy of the commonsA big part of the trouble is that the gains from the overuse of antibiotics are private, whereas the losses are public.
Owing to these designs, nearly all studies (88%) suffered from the well-described and problematic disease-verification bias (Begg and Greenes, 1983; Lijmer et al, 1999; Mol et al, 2003; Whiting et al, 2004; Rutjes et al, 2005; Biesheuvel et al, 2008).
In a continued free fall of free will and personal responsibility, America is ever hungry to call a problematic habit a disease and look for a magic pill to treat it.
The casual user is not equipped to select from these non-orthogonal ontologies and selecting a more specific child term is more problematic; the Disease Ontology alone has 16 subclasses.
