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However, trastuzumab mono-therapy shows a response rate of no more than 30% in palliative setting [ 4], and there is still a problem of primary or acquired resistance even with combination regimens.
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Are we talking about a problem of primary-care management?
This is particularly difficult because the opioid crisis has moved well beyond just a problem of prescribed pills in primary care; it is now fueled by heroin and illicitly obtained drugs like fentanyl, and deaths are escalating.
Vladeck, speaking at a Senate Finance Committee hearing, noted that the current payment system is "central to the income problem of primary care physicians".
I was somewhat skeptical when Senator Bernie Sanders, an independent from Vermont, told me that these centers (there are 39 sites of various size in the state) had "essentially solved the problem of primary care" for local residents.
The use of ePTFE-covered stent grafts has dealt with the main problem of primary TIPS dysfunction [ 13].
Thus, our calculations, while not addressing the problem of primary resistance, are able to explain secondary resistance in advanced GIST.
But focusing on the absurdity of the primary calendar obscures a problem of greater significance: not all voters are equal.
However, an early follow-up visit can help prevent problems of primary compliance, which in post-acute myocardial infarct patients can be as high as 17.7% in cardiology medication [ 23].
To address the problems of primary science education and to adapt Western educational theories to a CHC, curriculum designs are needed that take characteristics of cultures into consideration (Nguyen et al. 2005; Örtenblad, Babur and Kumari 2012).
It attempts to formulate the problems of primary importance faced by process systems engineers in their attempt to assist the design of highly reliable, flexible and controllable MPCRS.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com