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For the analysis based on PhyloCon, the orthologous groups that are compared and combined result from a prior selection of orthologous mate-pairs by co-expression analysis.
Consistent with results from our in silico analysis, the microsatellite experimental data revealed larger alleles in 9930 compared to Gy14 for most SSRs tested (62.4% of all polymorphic SSRs), thus providing empirical support for our hypothesis regarding a bias due to a prior selection of larger microsatellite loci in 9930.
This method, unlike GIMME, does not require a prior selection of expression thresholds and instead uses MILP and the statistical significance of changes in gene-expression to develop a metabolic model that recreates the measured expression dynamics while ensuring that the FBA model maintains previously determined threshold functionality.
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Similar yields of polymorphic segregating SNPs have been found when mapping SNPs in other forest trees without any prior selection of polymorphic SNPs between the parents [ 10, 29].
SAGE provides a statistical description of the mRNA population present in a cell without prior selection of the genes to be studied, and this constitutes a major advantage.
The SAGE method provides a statistical description of the mRNA population present in a cell without prior selection of the genes to be studied, and this constitutes a major advantage [ 17].
Building of a thematic core collection was here defined by prior selection of accessions which are diverse for the trait of interest, and then by pairwise genetic distances, estimated by DNA polymorphism analysis at molecular marker loci.
Building of a thematic core collection was here defined by prior selection of accessions which are diverse for the trait of interest (thematic collection), and then by pairwise genetic distances, estimated by DNA polymorphism analysis at molecular marker loci.
However, it is important to keep in mind that the prior selection of only three features could possibly constitute an implicit a priori variable selection that could lead to biased cross-validation-based accuracy estimates (Ambroise & McLachlan, 2002).
Although the prior selection of genetically informative markers allowed a high rate of correct assignment there were, nonetheless, a few instances of incorrect assignment of individuals.
The specific interest of this work was first focusing on global gene expression regulation without prior selection of transcripts for association with a particular trait, and second using a family structured population that enabled genetic analysis.
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