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Replication of the in vivo mechanical patterns or parameters is also a prior challenge to confine the understanding how mechanomics works for cells.
The ability of the two variants to colonize was also tested using a chinchilla model and no difference was observed unless there was a prior challenge with influenza A virus [17].
A prior challenge with BAY606583 enhanced the chemotherapeutic effect of TMZ: the percentage of reduction of both the area occupied by and the number of CSC-derived neurospheres was significantly higher in the BAY606583 TMZ-treated cells than in the cells treated with TMZ alone (% of reduction of the area occupied BAY606583 TMZ-treatedTMZ alone=57.3±4.3% BAY606583–TMZ=70.2±0.6% P<0.001).
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She calls him "brother", but a week ago called him "little boy" and chastised him for his part in a prior leadership challenge, this seven-month old government's second.
One explanation for this might be that patients contract certain prevailing bacterial strains (so-called common types) more often, and a prior antigen challenge and subsequent humoral response may play a role.
In a different approach to combat V. cholerae, an E. coli strain expressing a ganglioside GM mimic (the target of cholera toxin) successfully reduced virulence after prior challenge.
This significant degree of correspondence between a prior endotoxin challenged population and the present volunteers group confirms the fidelity of our baseline and endotoxin challenged-subjects analysis.
This article discusses a retrospective study of 8,711 women, delivering at ≥20 weeks' gestation, who had a prenatal 2-h 75-g OGTT without a prior 50-g challenge and were not treated with insulin, glyburide, diet, and/or exercise during pregnancy.
Similarly, systemic (intraperitoneal) administration of recombinant activin A prior to each allergen challenge suppressed allergic airway inflammation [ 60].
Implementing the analysis with such a prior would be a significant challenge computationally; we hypothesize that it will be difficult to derive a well-behaved MCMC approach.
Patients who have had a prior HBV infection clearly present a challenge for clinicians.
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