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Discover LudwigThe phrase "a principal problem in" is correct and usable in written English.
It can be used when discussing a major issue or challenge within a specific context or field.
Example: "A principal problem in urban development is the lack of affordable housing."
Alternatives: "a major issue in" or "a key challenge in".
Exact(3)
A principal problem in exploring the lunar ionosphere using the AKR is calculating theoretical phase patterns accurately.
A principal problem in any system of analysis of digital images of PCO is that of artefactual light reflections spoiling the image.
Progression of chronic kidney disease remains a principal problem in clinical nephrology and there is a pressing need for novel therapeutics and biomarkers.
Similar(57)
A shrewd observer would argue that the principal problem in poor countries is the absence of production capabilities.
Ashe's principal problem in tennis has been consistency.
Dr. McAllister said that in Dr. Taylor's case "the principal problem in escalating it to humans is one of scale, not of cell biology, and that is an easier problem to solve potentially".
The principal problem in the watermarking domain is the compromise between imperceptibility, robustness, and the integration rate.
The principal problem in this study is that the Scottish database did not record the indications for induction of labor so that unless maternal or fetal pathology was specifically mentioned, the induction of labor was considered to be elective.
Based on methodical, but also on principal problems in deriving conclusions about hormone effects from correlational designs, the present study investigated hemispheric asymmetries in postmenopausal women, who received hormone replacement either with E alone (E group, n = 32), an E P combination (E P group, n = 29) or no hormone substitution (control group, n = 31).
One of the principal problems in intelligent control system design is tying together various methods and models traditionally used in robotics and aimed at solving such tasks as dynamics modeling, control signal generation, location and mapping, path planning, etc. with the methods of behavior modeling and planning which are thoroughly studied in cognitive science.
One of the principal problems in Mexico City is the lack of housing.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com