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The phrase "a principal cause" is correct and usable in written English.
It can be used when discussing the main reason or factor contributing to a particular outcome or situation.
Example: "The researchers identified a principal cause of the decline in bee populations as the widespread use of pesticides."
Alternatives: "a primary reason" or "a major factor".
Exact(60)
Though overpopulation is a principal cause of both, it is rarely mentioned in relation to them.
"A principal cause is their common ownership by BAA," the commission said.
But that didn't prevent Reagan's victory and wasn't a principal cause of McCain's defeat.
A principal cause, for instance, is that people do not live so long.
The accumulating evidence has convinced most critics that the Civil Rights Act was a principal cause of black progress.
Every time I tried to pin down a principal cause for the Dreissena invasion, I was presented with another contender.
Here in Oklahoma, Gov. Frank Keating, also a Republican, diagnosed divorce as a principal cause of poverty in his state.
(A cap-and-trade system is currently in place for sulfur dioxide, a principal cause of acid rain).
Familial hypophosphatemia is a sex-linked inherited disorder that is a principal cause of rickets in the developed nations.
Diarrhea kills 1.6 million children each year — more, even, than malaria — and the pollution of drinking water with waste is a principal cause.
That organic matter contains carbon, which is therefore prevented from burning, combining with oxygen and becoming carbon dioxide -- a principal cause of greenhouse warming.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com