The phrase "a primary substrate of" is correct and usable in written English.
It can be used in scientific or technical contexts to describe a main substance or material that supports or underlies a process or reaction.
Example: "Glucose serves as a primary substrate of cellular respiration, providing the necessary energy for metabolic processes."
Alternatives: "a main component of" or "a key material in".
Since Trx is a primary substrate of TR1 and since other Sec-deficient TR1 have demonstrated oxidative stress, we measured the Trx redox status to determine if the Sec-deficient C-terminal mutant TR1 altered the redox status of Trx.
Interestingly, all cellular and histopathologic abnormalities observed in Skp2-deficient mice are abolished in Skp2/p27 double knockout mice, indicating that p27 is a primary substrate of Skp2 in vivo (K Nakayama, personal communication).
The posterior superior temporal lobe has been implicated as a primary substrate for constructing sound-based representations of speech [21].
Phytic acid biosynthesis constitutes a uniquely complex process, consisting of a primary substrate, Ins, and a number of interjecting secondary Ins polyphosphate substrates from other sources and pathways [ 11, 12].
Acetate or toluene was added to the batches to promote biomass growth, suggesting that they could serve as a primary substrate in a cometabolic transformation of the pharmaceuticals.
Looking back at previous paragraphs, it appears that the cell assembly model implies that the neurons in the core part of DNAs, most of which are localized in higher multimodal cortices, are the primary substrate of a range of higher sophisticated cognitive mechanisms.
Previously, we reported that ICV infusion of 1 mg/kg hASM was the lowest effective dose to reduce lysosomal accumulation of sphingomylein (the primary substrate of hASM) in a mouse model of Niemann Pick A disease [16].
The primary substrate of laccases is lignin, an amorphous, complex cross-linked polymer consisting of phenylpropane units (Claus 2004; Moilanen et al. 2011).
Crystal structure of the FTO protein recently confirmed this, and indicated that single-stranded RNA is the primary substrate of FTO [16].
Deciduous leaves, the primary substrate of aquatic hyphomycetes, are highly seasonal in abundance in temperate climates [12] [14], with leaves most abundant in late autumn and winter and least abundant in summer and early fall [15].
Hazlett et al. [30] and Desrosiers et al. [31] revealed that TpTroA has high binding affinity for both Zn2+ and Mn2+, but Zn2+ is considered to be the primary substrate of TpTroA [32].
