Progressive collapse is a situation where local failure of a primary structural component leads to the collapse of adjoining members, which in turn leads to spread of collapse.
The situation in which there is local failure of a primary structural component that leads to the collapse of adjoining members is called progressive collapse, and this, in turn, leads to total collapse or the collapse of a disproportionately large part of the affected structure (ASCE 2010).
Being a primary structural component and due to its critical roles in both late and early stages of the HIV replication cycle, CA has attracted increased interest as a drug discovery target in recent years.
In a broad view of these biosynthetic scaffolds, the polymer nanofiber component serves as a primary structural component and the DECM nanoparticles serve as a modular component selected based on the desired bioactivity for a specific application.
Chitin, an N-acetyl-D-glucosamine (GlcNAc) homopolymer, is the primary structural component of fungal cell walls and is recognized as a PAMP by plant cell surface receptors that contain extracellular lysin motifs (LysMs) (Felix et al., 1993; Shibuya et al., 1993; Shibuya et al., 1996; Kombrink et al., 2011).
Caveolin-1 (CAV1), the primary structural component of specialized plasma membrane microdomains called caveolae, is a crucial regulator of tissue fibrosis.
Furthermore, CAV1, the primary structural component of plasma membrane caveolae, has independently been identified as a crucial inhibitor of tissue fibrosis and has been functionally implicated in the pathogenesis of various fibrotic disorders including kidney fibrosis [ 17].
Among other functions, it is the primary structural component of the eukaryotic flagellum.
Caveolin 1 (Cav-1) is the primary structural component of cell membrane invaginations called 'caveolae'caveolae
As the primary structural component of the plant cell wall, cellulose forms the cores of plant cell wall microfibrils.
In ligament, groups of fibrils form fibers and it is these fiber bundles that form fascicles; the primary structural component of the tissue.
