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As illustrated in Fig. 3, the scoring technique included three processes: (1) a primary screening of recovery initiatives; (2) an expert evaluation; and (3) calculation of the degree of inclusion of PAVR measures in recovery.
The main aim of this work was to evaluate the effect of doxorubicin in complex with C60 fullerene (C60 + Dox) on the growth and metastasis of Lewis lung carcinoma in mice and to perform a primary screening of the potential mechanisms of C60 + Dox complex action.
Data from NB patient tumor samples (GSE12460) were used to make a primary screening of lncRNAs associated with NB.
The goal of the present work was to develop a simple format array able to perform a primary screening of the mutations occurring in the most frequently affected codons of the TP53 gene.
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In a primary screen of 461 deficiencies collectively uncovering ∼50% of the Drosophila genome, we identified twelve intervals harboring Rho1-interacting genes.
A primary screen of 21,121 siRNA pools targeting most genes in the human genome identified 336 (1.6%) siRNAs that caused a significant increase in monopolar mitotic arrest in 60 nM K5I.
Our search results underwent a primary screen of titles and abstracts to identify any recent study that addressed breast cancer risk in relation to lactation history or more broadly, 'reproductive factors.' Any study identified in the primary screen as potentially eligible for inclusion then was assessed in a full-text screen according to predetermined inclusion and exclusion criteria.
Therefore a primary screen of these codons would be attractive.
Mycobacterium bovis BCG was used as a surrogate avirulent mycobacteria to safely handle a primary screen of over 600,000 compounds.
Thus, to stringently select for compounds that represent biologically relevant hits with respect to the phenotypic screen used, all 112 autofluorescent compounds were excluded from further analysis, identifying three hits from a primary screen of 6,764 molecules (Fig. 3B).
We set out to determine whether the addition of histopathology to a primary screen of targeted knockouts in a large-scale high-throughput pipeline was scientifically valuable, feasible and cost effective; a study that is relevant and timely given the ongoing efforts of the IMPC (Kim et al., 2010; Brown and Moore, 2012).
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CEO of Professional Science Editing for Scientists @ prosciediting.com