The phrase "a primary problem with" is correct and usable in written English.
It can be used when discussing a significant issue or challenge related to a particular subject or situation.
Example: "A primary problem with the current policy is its lack of clarity, which leads to confusion among employees."
Alternatives: "a major issue with" or "a key concern regarding".
A primary problem with modern godparenting is no one knows what to do.
A primary problem with these transactions is that the market is illiquid: parties cannot identify holders of relevant portfolios, they cannot agree on the value of portfolios, and the specter of litigation taints every negotiation.
"Infertile women have a primary problem with their ovaries and IVF has nothing to do with it," Kallen told Reuters Health.
We include the prep statistic because it overcomes a primary problem with null hypothesis statistical tests (i.e., the inability to accept or reject the null hypothesis), and it also provides a measure of the probability of replicability that is of primary importance in all research, but especially when considering small-n research such as that presented here.
Often a primary problem with rare bone diseases remains to be a lack of understanding of the underlying mechanism.
A primary problem with these clinical tools is that they do not factor the functional status of the patient [ 62].
A primary problem faced when dealing with protein function, as pointed out in [ 22], s defining the scope and function.
93 The indication for lubiprostone in patients with a primary problem of PFD is not established.
For example, many of the control patients were admitted postoperatively, while the septic cases were predominantly medical patients admitted with a primary problem of infection and organ dysfunction.
The result was not only a partisan bill but an unbalanced one that did almost nothing to address the primary problem with health care - soaring costs.
The primary problem with fund managers is that, in a marketplace focused on the short term, they have little incentive to make and act on their judgments about a company's or industry's long-term prospects.
