Sentence examples for a primary mediator from inspiring English sources

In this study, we demonstrated that NKDCs, functioning as immunostimulatory DCs, could be a primary mediator of the α-GC-mediated immune response.

It also supports the biological role for HBP as a primary mediator of vascular leakage, an important pathophysiological mechanism in septic shock.

α-Amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor is a primary mediator of fast glutamatergic excitatory signaling in the brain and has been implicated in diverse neuropsychiatric diseases.

Prophages are a primary mediator of GAS intra- and inter-serotype differences in virulence factor content [80].

The emerging idea is that TNFα is not a primary mediator of NASH but influences its development [9], [10], [12].

Recently, we identified a gastrin-releasing peptide (GRP) system in the lumbar spinal cord that is a primary mediator for male reproductive functions.

Although we cannot exclude with certainty the role of t-Ag and other T'- proteins, based upon our results it is reasonable to speculate that T-Ag may be the primary mediator of a metastatic phenotype in colon cancer cells, and some of these effects may directly or indirectly be influenced by the activation of AKT/MAPK pathways [44], [45].

A recent report has indicated that VEGF-C, the primary mediator of lymphangiogenesis, is a downstream factor regulated by SIRT1 [ 25].

We revised the Results and Discussion to better set up and then state our argument against an activation chain as the primary mediator of the grooming sequence.

Jak2 tyrosine kinase serves as a primary functional mediator of growth hormone, prolactin and interleukin signaling.

In eukaryotic cells, hypoxia-inducible factor-1 (HIF-1) is a primary transcriptional mediator of the hypoxic response and master regulator of O2 homeostasis [ 26].