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Especially in Crohn's disease the altered epithelial barrier is believed to be a primary factor in the development of the disease [11].
The concern over physical inactivity is justified because it is a primary factor in the development of many chronic diseases, which not only lead to productivity loss, but also increase the public health care burden [ 2].
Sarcopenia, defined as the aging-related loss of muscle mass and/or strength, 1– 3 has been shown to be a primary factor in the development of frailty, accounting for falls and loss of independence.
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A rapid increase in trade was a primary factor in the 1990's expansion.
This, he said, is a primary factor in the killing of civilians.
Not surprisingly, hyperarousal is a primary factor in the contemporary epidemic of insomnia.
These observations suggest that catecholamine resistance of lipolysis may be an important early, and perhaps primary factor, in the development of obesity.
In some cases soil is a primary factor in inducing development of scrubland vegetation.
The models developed by Adam Frank, an astrophysicist at the University of Rochester, and his colleagues look at two primary factors in the development of a technical civilization: population size and energy use.
The National Institute for Justice lists being in a sorority as a primary factor in increased sexual assault risk.
I doubt that this system of education is a primary factor in rising drug costs.
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