To the extent that a primary contributor to the expression level of a gene in cancerous tissue is the corresponding gene copy number, this type of analysis, using DNA copy number microarrays, could be considered as a proxy for RNA microarrays.
A primary objective was to probe the extent to which DTC genetic testing can provide meaningful results to people who decide to purchase those tests privately.
That is, to a large extent, no longer a primary issue.
(m)Relevant metropolitan statistical area (RMSA) means an MSA, a primary MSA, or a consolidated MSA that is not comprised of designated Primary MSAs to the extent that these terms are defined and applied by the Office of Management and Budget.
In contrast, α, β-unsaturated ketones are soft electrophiles that preferentially react with soft nucleophiles, including cysteine thiols and to a lesser extent primary and secondary amines of lysine and histidine residues, respectively.
Staff Assessment of enGagement with Evidence (SAGE) is an objective measure of the primary outcome the extent to which agencies apply research findings in the development of the policy and programme documents they produce.
The primary tumor extent (T1 T4) and lymph node status were determined using the American Joint Committee on Cancer criteria [ 19].
Furthermore, our results demonstrate that BAX mRNA expression is significantly associated with various clinicopathological parameters, including primary tumor extent, regional lymph node status, and presence of distant metastases.
A subsequent study (Anderton et al. 2008) confirmed that the gene was methylated in medulloblastoma cell lines but not in 16 primary tumors studied, suggesting that methylation may concern cultured cells and not to occur to a great extent in primary tumors.
This minimum dataset was based on data known to be routinely collected in secondary care clinics assessing patients with cognitive disorders and to a lesser extent in primary care (for example, functional status data may not be routinely recorded in primary care notes).
Some of these differences did follow, to a certain extent, the primary care model.
