The phrase "a primary decrease in" is correct and usable in written English.
It can be used in contexts discussing changes in quantity, value, or intensity, particularly in fields like economics, biology, or statistics.
Example: "The study revealed a primary decrease in the population of the species over the last decade."
Alternatives: "a significant reduction in" or "a major decline in".
Theoretically, a primary decrease in bone formation and decreased buffering capacity for calcium, with consequent increased urinary expression of dietary calcium could account for the relationship between osteopenia and hypercalciuria in GPRC6A−/− mice.
IMAT can be present in conditions characterized by an increase in muscle mass, such as in acromegaly [48], but it is particularly evident in conditions characterized by a primary decrease in the muscle mass as in myopaties, aging [49], and sedentary young subjects.
Alternatively, increased hematocrit levels and, therefore, increased viscosity may be a compensatory response to a primary decrease in oxidative capacity.
Reduced serum concentrations of IGFBP-3 can result from a primary decrease in IGFBP-3 production, or secondarily, due to a reduction in IGF-I.
We recently documented a primary decrease in peripheral impedance and an increase in peripheral compliance associated with a decrease in central aortic compliance in a porcine model of early endotoxic shock [ 10].
These responses are often characterized by primary decreases in important indices of cardiac and thermoregulatory function, along with secondary decreases in associated parameters.
This study showed that the development of an IEP leads to a shift from secondary care to primary care, a decrease in waiting/consultation times, a decrease in self-referrals, and increased patient satisfaction with telephone contact with care providers.
In the rat cortical primary neurons, a decrease in peroxisome proliferator-activated receptor-gamma coactivator- (PGC-) 1 α was observed, suggesting that SIRT1 activity was increased following resveratrol treatment of primary neurons.
The leuprolide acetate trial that led to US approval sought as its primary endpoint a decrease in total serum testosterone to ≤50 ng/dL on at least two consecutive measurements taken 1 week apart.
Moreover, the frequency of mucilage outbreaks in the Adriatic Sea has increased in the last 2 decades concurrently with a significant decrease in primary production.
The suppression of ocean upwelling and the rise in SST cause a marked decrease in primary productivity with ecological consequences for the entire marine food web [5].
