The calculations presented here demonstrated that the depth of the recessed electrode required to achieve a uniform primary current distribution was twice the electrode radius.
A non-dimensional primary current distribution model of the micro-electroporation channel shows that while increasing insulator thickness results in smaller electric field magnitudes, electroporation can still be performed with insulators thick enough to be made with microfabrication techniques.
A non-dimensional primary current distribution model of the micro-electroporation channel showed that decreasing channel height results in an exponential increase in the electric field magnitudes, and that cells experience exponentially greater electric field magnitudes the closer they are to the channel walls [28].
Two models were developed to understand these effects: (1) a modified, non-dimensional, primary current distribution model of a micro-electroporation channel, and (2) a secondary current distribution model of the singularity-induced micro-electroporation configuration with platinum electrodes and water electrolyte.
The design tool consists of a mathematical model that reproduces the transient behavior of a transformer when the primary current is generated by the discharge of a capacitor bank.
In this paper we present (1) a modified, non-dimensional, primary current distribution model to analyze the effect of insulator thickness on the micro-electroporation channel, and (2) a secondary current distribution model of the singularity-induced micro-electroporation configuration with platinum electrodes and water electrolyte.
Instantaneous tomographic estimates were stored for later statistical analysis as a three-dimensional distribution of primary current density, J (r, t), in an array of grid points (17 × 17 × 17), covering the entire brain.
However, during the switching period, the leakage flux caused by imperfect coupling and the sudden change in primary current induce a voltage across the opening switch which exceeds the affordability of modern solid-state switches.
A previously developed, non-dimensional, primary current distribution model was modified to analyze the effect of insulator thickness on the electric field distribution of a micro-electroporation channel.
