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In summary, EGFR is well validated as a primary contributor of HGG initiation and progression [ 8].
Epidermal Growth Factor Receptor (EGFR) is well validated as a primary contributor of glioma initiation and progression.
The presence of endotoxin in the blood stream is a primary contributor of septic shock, and several proinflammatory cytokines such as TNF- α and IL-6 can contribute to cardiac dysfunction during sepsis [ 5, 6].
Although excessive ROS production has been indicated as a primary contributor of I/R injury, ROS-targeted therapies including antioxidant treatments have yielded mixed results in attenuating I/R-induced damage [ 19].
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It is a primary contributor to the regulation of exchange of nutrients and water between tissues and blood.
Cardiovascular disease is the leading cause of mortality and a primary contributor to the burden of disease worldwide (Lopez et al. 2006).
While the elastic prestress had no effect on the surface texture, it was a primary contributor to the magnitude of surface residual stress, which increased with an increase in the elastic prestress.
The arrival of Protestant missionaries on a large scale beginning in 1814 was a primary contributor to the development of political awareness among Sri Lankan Tamils.
The arrival of Protestant missionaries on a large scale to Sri Lanka (then called Ceylon), beginning in 1814, was a primary contributor to the development of political awareness among Tamils.
The calpain susceptibilities of SMNΔ7 and SMNΔ7+EMLA proteins were also similar to that of WT (Figs. 4A,B, and S5), indicating that calpain cleavage is not a primary contributor to the instability of SMNΔ7.
In other cardiac diseases (such as hypertension), globalized fibrosis is likely a primary contributor to the progression of congestive heart failure.
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