Sentence examples for a primary consequence from inspiring English sources

A primary consequence of RNA toxicity in DM is dysfunction of two classes of RNA binding proteins, which leads to abnormal regulation of alternative splicing, or spliceopathy, of select genes.

These data have to be carefully evaluated when used to monitor disease evolution [45], as penetration of death probes might be a primary consequence of membrane permeabilization during isolation rather than a physiological feature of the disease [46].

Is there potential harm to the donor (a hastening of death as a primary consequence)?

A primary consequence of Babesia infections are haemostasis disturbances together with inflammation-related complications.

Alteration of the hypothalamic-pituitary-adrenocortical (HPA) axis is a primary consequence observed in the offspring [9].

26 Whether complex I deficiency is a primary consequence of the disease or a secondary adaption is a question that remains to be addressed.

A critical question is whether degradation is a consequence of a primary effect on translation.

This suggested that membrane disruption was a primary event rather than a consequence of swelling after failure of membrane ion pumps.

While fMRI, EEG, and PET data suggest medial parietal/posterior cingulate cortex involvement in early AD, it is not known if this is a primary event or a secondary consequence of MTL pathology, such as neurofibrillary tangle deposition, which occurs early on in the disease [37].

Next, we investigated whether Rnf12 upregulation is a primary, early consequence of Nanog depletion.

These data are significant because they indicate the importance of mitochondrial Ca2+ handling over the transport of other ions or solutes as a primary physiological consequence of the Mcl-1/VDAC interaction.