This model places the emphasis on the secondary accumulation of autophagy substrates as a key determinant of cell death, rather than on the primary accumulation of lysosomal substrates.
"In those days everyone in Russia was engaged in the primary accumulation of capital," Khodorkovsky recalls about the anarchic Yeltsin years.
However, the complexes (oMWCNTs-SP-A/B) could improve captures of oMWCNTs (1 to 10 μm, Figure 1) on the pulmonary capillary bed, leading to the primary accumulation of oMWCNTs in the lungs (Figure 9A) and eventually forming granuloma and longtime retention [19].
Before the development of industrial agriculture, the primary accumulation of wealth was the land sales, from the founding of the United States until 1840.
The primary accumulation of abnormal COMP also appears to result in the secondary retention of type IX collagen and other proteins, eventually producing large insoluble "inclusion bodies" [ Vranka et al., 2001].
Staining with the J2 antibody detected similar amounts of dsRNA in the tdp-1 ok803 tdp-1 ok80319) double-mutant as comparde-1 ne219tdp-1(ok803) rde-1 ne219nt worms (Fig 7C), confirming that the mutation in rdouble-mutantsuppress the primasy acomparedion of dsRNA.
Analysis across all sampling sites indicated that the crayfish digestive organ (hepatopancreas) was the primary accumulation site of the majority of studied metals.
The primary accumulation tissues/organs of Cu-labeled targeted micelles included the liver, tumor, spleen, kidneys, and intestines.
The kidney is also a primary site of accumulation and toxicity of inorganic mercury.
The action of Mahagonny unfolds against a backdrop formed not by the "alienated labour" that Marx defined as the basis of late capitalism, but such activities as logging, prospecting and prostitution – all of which, in Marxist terms, constitute forms of primary accumulation.
