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The phrase "a pretty significant amount" is correct and usable in written English.
It can be used when discussing a quantity that is notably large or important, often in informal contexts.
Example: "The project received a pretty significant amount of funding, which will help us achieve our goals."
Alternatives: "a considerable amount" or "a substantial amount."
Exact(11)
We know it uses a pretty significant amount of energy - not as much as running a 10K but more than people think.
"I think he's going devote a pretty significant amount of his political resources to bear on this question," he said of President Obama.
But we have to remember that a pretty significant amount of time (in day-to-day office years) has passed and so I don't think it's supposed to have the emotional gravity it had last season when Joan emerges from the bedroom, having already slept with Herb from Jaguar, Don too late to stop it.
Still, that is a pretty significant amount of content from just one partner.
Baobab Studios has been getting a pretty significant amount of attention from the gatekeepers of the VR industry as well.
That's actually a pretty significant amount for the company; for the entire (fiscal) year 2009, comScore reported revenues of $127.7 million, up from $117.4 million the year before, an 8.8% increase.
Similar(49)
Then there's income splitting for families and seniors, meaning they can reduce their tax burden by a pretty significant yearly amount.
"We woke up the next morning having had a fairly significant amount to drink and said, 'Wow, we feel pretty good.
But declaring that the three quarters of the British public who buy organic food for a wide variety of good reasons are simply making a "life-style" choice may at least amount to a pretty significant self-inflicted injury.
That's an average of 4.8 times daily, which amounts to a pretty significant number of communications to the general public during the last two months.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com