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This indicates that some aspects of protein function violate the assumption that sequence determines a specific structure as a prerequisite for function, and is in line with other results reported recently [38].
Under our experimental conditions, PTTG2 was unable to bind separase, a prerequisite to function as a securin.
We found that the formation of a chondrocyte sheet structure enhanced transforming growth factor-β secretion from the cells [ 37], which implies that maintaining the membranous structure after cryopreservation is a prerequisite for function.
Consistent with the assumed importance of MLO signalling for rust resistance, some genes important for MLO function as e.g. "calmodulin", involved in calcium signalling as a prerequisite for MLO function [ 51], were down-regulated in the susceptible genotype (group G).
Cell adhesion is a prerequisite for VFF function regulation and cell communication.
Repair of the damage is a prerequisite to gene function.
The interaction with bacterial membranes is a prerequisite for AMP function.
The transmembrane domains mediate oligomerization of LMP1 molecules in the plasma membrane, a prerequisite for LMP1 function [1], [9].
AMP function has been thought to involve direct binding to the lipid bilayer, and the interaction with bacterial membranes is a prerequisite for AMP function.
It is known for the Drosophila GAGA-motif binding proteins that dimerization is a prerequisite for their function [5], [34], [35].
Finally, by immunoprecipitation, we showed that coxsackieviral polymerase 3D was post-translationally modified by ubiquitination and such modification might be a prerequisite for its function in transcriptional regulation of viral genome.
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