Sentence examples for a premature decrease in from inspiring English sources

Deregulated Myc therefore leads to a premature decrease in Cav1, thereby removing its restraining influence on prolactin receptor-Janus kinase2-Stat5 signaling.

Depletion of these PSCs in an Ins/Igf-dependent manner may lead to a premature decrease in VSELs and the regenerative potential of monopotent tissue-committed stem cells (TCSCs) that, as VSEL progeny, directly rejuvenate tissues.

A premature decrease in the NSC pool owing to aging suggests that these NSCs have no self-renewal capacity and/or are programmed to complete only a limited number of divisions (Sii-Felice et al, 2008).

However, because p16 Ink4a -KO mice die of cancer long before they reach the age at which most normal mice experience a decrease in SMG function, we asked whether p16 Ink4a deficiency can rescue the premature decrease in SMG function in Bmi-1-KO mice.

This energy hole problem significantly increases the unbalanced energy usage among SNs and leads to premature decrease in network lifetime.

For example, we estimated twice as many deaths avoided in Seattle, Miami, and San Francisco during 2006 compared with 2005 or 2007, but a 50% decrease in premature mortality in Chicago and Detroit.

The results agree with those of previous adult studies on NIV-NAVA, demonstrating a decrease in premature and delayed cycling, abolishment of ineffective effort, reduction of asynchrony events, and a preserved CO2 clearance [ 34- 36].

Electrocardiographic (ECG) records and Doppler echocardiography examination revealed ventricular premature beats and a decrease in left ventricular global and systolic function, respectively.

Indeed, CTIBL in patients with chemotherapy-induced premature menopause leads to a marked decrease in BMD within a short period of time [ 16].

That study demonstrated that inactivation of miRNA synthesis in adult animas led to a major decrease in lifespan and premature aging (a phenotype very similar to mir-71 mutants).

The FVB/N mouse strain has been previously characterized to undergo premature thymic involution, with a sharp decrease in cellularity and disruption of the cortico-medullary junction as early as 5 months, compared to 12 15 months in C57BL/6 mice 25.