Sentence examples for a preferential target from inspiring English sources

Therefore, dysfunction of mitochondria would be a preferential target of many antineoplastic agents [22 25].

We design a laser pulse which drives a racemate of oriented atropisomers at low temperature to a preferential target enantiomer.

Since these viruses can either infect or co-infect humans, virus/HSPGs interaction is a preferential target for the development of wide-spectrum antiviral microbicides.

The protosplice is defined as a preferential target sequence for insertion, involving the spliceosome machinery [43].

The latter may simply reflect the possibility that precursor cells constitute a preferential target for v-Src-induced transformation and are subsequently maintained in their undifferentiated state, as a consequence of their sustained division.

The fact that surface nucleolin is constantly and abundantly expressed on the surface of tumor cells, makes them a preferential target for the inhibitory action of anticancer agents that target surface nucleolin.

The first is a preferential targeting of those elements to the regions harboring those genes.

We found a marked inhibition of sphere formation by the combination of chemotherapy and the Chk1 inhibitor, thus confirming a preferential targeting of the clonally expanding cells.

Moreover, the overlap of OATP1C1 expression with Aquaporin 4 (Roberts et al. 2008) suggests a preferential targeting of the transporter to astroglial end feet of the blood brain barrier.

Whereas P42-TAT could be detected in different neuronal populations (NeuN cells Figure  3) or cilia cells (Additional file 1: Figure S2), but also in astrocytes (data not shown), we could not identify a preferential targeting.

Following 48 h of incubation with T-DM1, HER2-positive breast cancer cell lines like SK-BR-3 and BT-474 dose-dependently lost their clonogenic potential, which suggests a selective depletion of clonogenic cells and thus a preferential targeting of CSC by T-DM1.