Sentence examples for a preferential benefit from inspiring English sources

Pravastatin might have a preferential benefit among primary prevention patients at high risk of diabetes.

Interestingly, in the setting of advanced breast cancer receiving bevacizumab, certain VEGF genotypes were associated with hypertension and appeared to derive a preferential benefit (Schneider et al, 2008).

In particular we are interested to find out if over-expression of ErbB-2 results in a preferential benefit from anastrozole, and we can therefore be selective in our choice of adjuvant therapy according to the specific tumour phenotype.

In this retrospective study, single-agent lenalidomide had a significant preferential benefit in non-GCB-like as compared to GCB-like DLBCL (ORR 52.9% versus 8.7%).

Therefore, in an attempt to predict preferential benefit from combined AKT inhibitor/trastuzumab therapy, exploratory biomarker analyses may need to consider the polygenic nature of trastuzumab resistance and assess multiple aberrations in the HER2 signaling pathway in each tumor.

Similarly in the subgroup with co-morbid tics, no preferential benefit was noted for quetiapine.

Lapatinib has shown preferential benefit for Her2 amplified breast cancer patients compared with patients with normal level of Her2 (Konecny et al, 2006).

The outcome of the first controlled study in this area with the antipsychotic haloperidol demonstrated preferential benefit for refractory OCD subjects with co-morbid tic disorder [ 20].

The presence of HER2 in tumor tissues also adds predictive and prognostic information regarding shorter overall and disease-free survivals [ 4], preferential benefit from doxorubicin [ 5– 7], and possible resistance to tamoxifen [ 8– 10].

Despite efforts to identify predictors of preferential benefit from HER2-targeted therapies (e.g., truncated HER2, PTEN loss and SRC activation), HER2 protein overexpression and/or gene amplification remains the most important predictive factor of response to HER2-targeted therapies.

Application of a regional nerve block may have preferential benefits in areas where injection of local anesthesia is limited by anatomic considerations, concern for distortion of the tissues being closed, or benefit of proximal blockade to maximize site anesthesia when the distribution is appropriate.