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It also appears that smoking is not a predominant risk factor.
TRANSLATIONAL IMPACT Clinical issue Hypertension, a predominant risk factor for cardiovascular disease, has a complex etiology.
For instance, obesity is a predominant risk factor for women compared to men, but smoking still remains mostly a risk factor for men.
In families with hereditary pancreatitis, a cationic trypsinogen mutation is a predominant risk factor for the manifestation of chronic pancreatitis [ 1]. Almost all disease-associated mutations are located within the active enzyme ; three other gained interest, as they change the amino acid sequence of the trypsinogen activation peptide (TAP), but not the active trypsin molecule.
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As life-expectancy rises across the globe, the biological process of aging is an ever more predominant risk factor for the burden of disease, including metabolic, cardiovascular and neurodegenerative disease and cancer.
Having an indwelling urinary catheter was the predominant risk factor for 83% of patients, followed by receiving broad-spectrum antimicrobial drugs (75%), spending time in an intensive care unit (58%), having neutropenia (50%), and having a central venous catheter (CVC) (42%).
During a large epidemic of Clostridium difficile associated disease (CDAD) in the province of Quebec, receipt of fluoroquinolones emerged as the predominant risk factor for CDAD in a large cohort study of inpatients at the Centre Universitaire Hospitalier de Sherbrooke, a 683-bed tertiary-care hospital (20 ).
The predominant risk factor for patient delay is a lack of interpretation by patients of the serious nature of their symptoms.
To date, a number of risk factors have been identified for BMLs; one predominant risk factor is malalignment [ 18].
Moreover, aging is the predominant risk factor for cardiovascular diseases and contributes to a significantly worse outcome in patients with acute myocardial infarction [ 68].
Poorly controlled hypertension is the predominant risk factor for premature cardiovascular disease, with an estimated contribution of 54% in all cerebrovascular accidents (CVAs) and 47% of all coronary events globally [ 6].
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