Sentence examples for a predominant function in from inspiring English sources
This indicates that CAE1 is likely specifically involved or at least has a predominant function in root hair tip growth signaling.
As OST1 has a predominant function in relaying ABA signaling to stomatal closure, our subsequent analysis on putative targets will be focused on those enriched in the guard cells (Table S2).
Our findings suggest that FGFR1 specifically has a predominant function in FGF-2-promoted cartilage degeneration and OA pathophysiology.
The Gene Ontology categories involved (oxidoreductase activity, lipid and sugars storage/metabolism, Additional file 1: Table S2, S3) seem to indicate a predominant function in energy production and resource consumption.
Given that a predominant function of KDACs is to deacetylate lysines in core histones and thereby regulate gene expression (Shahbazian and Grunstein, 2007), we tested if compromising KDAC function led to reduction of HSP90 levels.
However, probably as a consequence of its predominant function in stimulating cell proliferation, deregulation of the TrkA pathway is common in cancers [ 5].
Its contributions to transcriptional regulation are mediated in several different ways: although PARP-1 can act as a promoter-specific co-regulator and by binding to specific enhancer sequences and insulators, its predominant function in transcription can probably be attributed to a modulatory influence on chromatin structure.
LRP2, also known as megalin, is a member of the lipoprotein receptor-related protein (LRP) family, with its predominant function in lipid metabolism through controlling the activity of lipoprotein lipase [ 7, 8].
Over the last years, increasing attention has been paid to skin engineering due to its predominant function in body integrity.
However, in the context of full-length sFRP1, it is clear that the CRD has the predominant function in repressing AR.
FoxO proteins identified in mammals, FoxO1, FoxO3a and FoxO4, constitute a newly characterized subfamily of the Forkhead/winged helix group of transcription factors and play a predominant role in mediating various functions of the PI3K/Akt pathway [16], [17].
