The phrase "a predisposition to the development of" is correct and usable in written English.
It can be used when discussing a tendency or inclination towards a particular condition or outcome, often in scientific or medical contexts.
Example: "Genetic factors can create a predisposition to the development of certain diseases."
Alternatives: "a tendency towards the emergence of" or "an inclination for the onset of".
Thus, this diaphragmatic defect may confer a predisposition to the development of a hernia in the context of increased intra-abdominal pressure.
In the heritable form, there is a predisposition to the development of non-ocular subsequent primary tumours (SPTs).
A predisposition to the development of certain specific and familial cancers is associated with the inheritance of a single mutated gene.
Yang et al. demonstrated that a deletion of both alleles of GSTT1 is a predisposition to the development of lung cancer in Asian populations [ 53].
The association of cigarette smoking with a predisposition to the development of microbial and viral infections of the airways is well recognized and carries a particularly high risk for invasive pneumococcal disease (IPD) [ 1, 2].
In mice, maternal obesity, T2D and a high-fat diet (HFD) during gestation increase adiposity and modify metabolism and blood pressure in adult offspring fed a control diet (CD), revealing a predisposition to the development of metabolic syndrome [ 77, 78].
Evidence from twin, family, and genetic studies supports a role for an inherited predisposition to the development of autism.
This report briefly reviews 2 recent studies designed to examine the hypothesis that there is a genetic predisposition to the development of arrhythmias associated with AMI.
These observations suggest a genetic predisposition to the development of long-QT intervals and torsade de pointes in the days after an AMI.
Mutations of RUNX1 have been identified in familial platelet disorder (FPD) along with a congenital predisposition to the development of acute myeloid leukemia (AML) [ 76].
Analysis of genetic predisposition to the development of chronic diseases in humans may be a significant and innovative addition to the existing approaches to evaluation of predisposition to different pathologies, including atherosclerotic disease and cancer.
