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The rats that pressed one lever learned that they would always get a predictable dose of sugary water.
The granisetron TD patch uses a drug-in-adhesive matrix diffusion method to deliver a predictable dose of granisetron for up to 7 days.
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This is probably safe, but a cut patch may not provide a predictable dose, said Dr. Michael C. Fiore, director of the tobacco research and intervention center at the University of Wisconsin Medical School.
The pharmacokinetics of midazolam in healthy populations has been well characterized, and pharmacodynamic studies demonstrate a predictable dose-response relationship.
In conclusion, this study confirms that lesogaberan works as a reflux inhibitor in a predictable, dose-dependent way.
He was trailed by a sizable legion but received only the predictable doses of "You're the man!" exclamations and general good wishes.
Although the toxicity of irinotecan or an EGFR inhibitor is predictable, dose adjustment should be made when necessary.
Type A reactions are predictable, dose-dependent and constitute about 80% of ADRs [ 125, 127].
SP1049C showed a predictable spectrum of toxicities at doses of 35 mg m−2 and above.
Data from phase I trials show that bortezomib induces predictable, dose-related, reversible inhibition of proteasome activity.
The pharmacokinetics of apixaban were predictable, dose-proportional and correlated with pharmacodynamic effects.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com