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IGF-II improved a rodent's memory only when administered in a precise window of time roughly within 24 hours after the foot shock which coincides with a stage in the learning process called "memory consolidation". That's a poorly understood transition period when a memory is still malleable but becoming more established and robust.
After customers have purchased a new flat-panel television set or computer, there is a precise window of time to offer them installation services where the rate of acceptance is significantly higher than it otherwise would be.
IGF-2 improved a rodent's memory only when administered in a precise window of time roughly within 24 hours after the foot shock which coincides with a stage in the learning process called "memory consolidation".
Without a precise "window of opportunity", spike generation depends on synaptic summation.
To further substantiate the existence of such a precise window we thus treated embryos with 2.5 µM of genistein at 5 hpf or 20 hpf and monitored apoptosis 7 hours after exposure (Figure 2A D).
Further, this photoactivatable ligand has the property of being an antagonist in the caged state and an agonist in the uncaged state, enabling a precise window for kinetic perturbation in single cells.
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This raises the possibility to predict RA development in high-risk populations and may further allow a more precise "window of opportunity" for early and effective treatment interventions.
The Peak Day method identifies a much more precise window of the periconceptional period than that used in most previous studies of periconceptional exposures.
Distractors presented contralateral to a visual target inhibit the generation of saccades within a precise temporal window (Buonocore & McIntosh, 2008; Reingold & Stampe, 2002; Walker, Kentridge, & Findlay, 1995).
Proteins, enzymes, fats, hormones and other compounds have to be absorbed, broken down, metabolised and produced in a precise time window to allow important processes such as growth, reproduction, metabolism, and cellular repair.
The progressive loss of WT1 in both ganglion and chromaffin cells, suggests its potential repressor role of differentiation in a precise temporal window during the development of the human PSNS and GENS.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com