However, a precise role of SlPti1 in plant pathogen resistance has remained unclear, owing to functional redundancy of different/additional Pti1 kinases.
To investigate a precise role of autophagy in CLP-induced sepsis, chloroquine, an autophagy inhibitor, was administered to the CLP-operated mice, and blood chemistry, pathology of the liver and survival were evaluated.
It is therefore imperative to link each individual gene with a precise role for a better understanding of the functions, the regulation and also the evolution of this key multifunctional enzyme family.
This study could provide insights to the role of insulin, insulin resistance, IGF-1 in carcinogenesis although a precise role and the extent of influence cannot be determined.
However, larger comparative studies of PWI and SWI are still needed to determine a more precise role of the new techniques in the grading of cerebral neoplasms.
SAA1 encodes the major acute-phase protein Serum Amyloid A (SAA), the precise role of which is still unclear despite reports suggesting a key role in the establishment and maintenance of inflammation notably as an antiapoptotic agent for neutrophils [ 36] and as an opsonin that would facilitate phagocytosis of gram-negative bacteria [ 37].
However, a definitive and precise role of mucins, the main secreted product of goblet cells, in host defense in intestinal nematode infection remains to be elucidated.
Because of the complexity of vitamin A metabolism, the precise role of CRBP-1 in retinoid signaling remains controversial, despite numerous studies conducted over the past three decades on its binding properties, three-dimensional structure, tissue localization, regulation of expression, involvement in retinal metabolism, and null mutation [ 120].
Although further study is needed to determine the precise role of Nm23/NDPK-A in malignant behavior of cells, Nm23/NDPK-A expression is potentially useful for assessing prognosis or selecting treatments in pancreatic cancer patients.
Moreover, if the precise role of Nm23/NDPK-A in malignant behavior of cells is elucidated, Nm23/NDPK-A might be therapeutic target.
The precise role of a public network company is also a political issue.
