Whatever the precise possibilities are that lead to increased compartmentalized calcium in podocyte foot processes, M132T is certainly one of them that together with other mechanisms requires us to consider large increase in TRPC6 channel currents as causative factors for early-onset FSGS.
This classic paper begins with some general remarks on the possibility of a precise definition of the concept of consequence.
While remaining within the tradition of the Austrian school of economic theory, in the technical form of decision theory (and a corresponding model of rationality), Neurath rejected the assumption of the value and even possibility of a precise calculus of utility involving an abstract and universal unit of calculation and uni-dimensionally commensurable alternatives.
This possibility of a precise localisation of IL-2 was a great tool to further analyse the function of the released IL-2.
When this is the case, transcriptograms offer the possibility of a precise expression measurement for functionally correlated gene sets and, consequently, increase reproducibility between laboratories.
This study demonstrates the possibility to derive a precise metric system for semantics of human experiences objectively from data collected without using human subjects.
Our paper describes, for the first time, a method allowing not only the isolation of a specific cell population in relation to the cytokine utilized but also the possibility to culture a precise cell type whose isolation is otherwise quite difficult.
On the other hand, the possibility to obtain a precise molecular diagnosis importantly impacts on the patients' management [2,3].
Finally, we would like to highlight that a successful characterisation of the transcriptional profile of well-identified precursor cells at a precise moment of development opens multiple possibilities concerning the analysis of the mechanisms underlying precursor cell determination.
Recently, a synthetic DNA-based small molecule triggered targeted transcriptional activation of pancreas-related genes to suggest the possibility of achieving desired cellular phenotype in a precise mode.
However, the approach reduces the possibility of carrying out geometrical reasoning and lacks a precise measurement of the detected movements.
