A part of America lives in a precipitous state of exploitation.
Corresponding to this increase of miR-34a, plasma expression of SIRT1, the major target of this microRNA, shows a precipitous reciprocal decrease starting at 4 months of age, while PBMCs exhibit a gradual decrease in SIRT1 from this age onward.
Untreated Npc1−/− mice began a precipitous weight loss beginning at 6 weeks of age, while combination-treated Npc1−/− mice gradually lost weight starting at 14 weeks (Fig. 1A).
A first performance of a new opera is the start of a precipitous journey.
The resulting Universal Music Group, with more than 30% of the market, became the global leader in the pop-music business at the start of a precipitous profit slide that has yet to end.
Like Krubera, Chevé starts with a precipitous drop: three thousand feet in less than half a mile.
Remarkably, not only the process has a precipitous character, but its onset starts the sooner the greater the amplitude of the triggering pulse: (sqrt{mathrm{field} mathrm{amplitude}} timestau_{mathrm{onset}} approxmathrm{const}).
A look at squad Nos. 12 through 23 reveals a precipitous drop in quality from the starting lineup.
Baedeker offered a running list of the physical markers that zipped past the train's broad windows: Dumbarton Castle, "strikingly situated on a precipitous rocky hill"; Craigendoran Pier, "an important starting point for steamers"; Helensburgh, "a favourite watering-place with extensive steamboat connections"; and Shandon, "with a large hydropathic establishment".
An L-shaped recovery reflects a precipitous decline, which is what we started to see in December 2007, followed by a prolonged period of large-scale unemployment and economic malaise, which is what we are seeing now.
Earliest Onsets occur when humidity is low and beginning a precipitous rise.
