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However, these measures would have been appropriate for an efficacy trial, whereas this effectiveness study aimed to measure outcomes in a pragmatic setting.
The trial benefited from a pragmatic setting, intention-to-treat analysis, blinding of outcome assessment and a broad socioeconomic spectrum of participants.
This is the first practical consensus on the role of probiotics in the management of the full range of lower GI symptoms in adults consulting clinicians in a pragmatic setting (particularly in primary care).
Analyses of network-level data using all eligible infants will provide a more accurate estimate of the effectiveness of an intervention in a pragmatic setting, rather than just a measure of efficacy proven in a controlled study setting.
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A pragmatic set of solutions are offered to support the transition to lower impact tourism development worldwide.
On the basis of a pragmatic set of Principles for the design of a regulatory scheme, it is proposed that countries apply existing regulatory arrangements and, where necessary, amend and extend them.
The survey tool was developed using a pragmatic set of 21 research indicators that includes those identified by the Delphi panel and the study participants themselves.
This cluster randomised trial examined a pragmatic set of interventions aiming to establish an integrated disease management programme, delivered by a multidisciplinary team to primary care patients with COPD.
As we have shown, pragmatic trial research consists of constant interaction between research and health care practices; this leads to adjustments in research with respect to what part of the study should be systematically performed and executed to answer to scientific demands and what part of the project could have a pragmatic set-up in the health care centres.
Comparative effectiveness outcomes with pragmatic designs in naturalistic settings for schizophrenia treatments are of increasing interest to healthcare providers because outcomes of treatment (both efficacy and safety) may vary significantly when identified in an explanatory setting compared with a naturalistic pragmatic setting.
Our ethnographic process evaluation showed that the opportunity of tailoring intervention procedures to routine care in a pragmatic trial setting did not result in a well-organised and well-implemented prevention programme.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com