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The phrase "a practical difficulty for" is correct and usable in written English.
It can be used when discussing challenges or obstacles that affect a person, group, or situation in a tangible way.
Example: "The new regulations present a practical difficulty for small businesses trying to comply with the changes."
Alternatives: "a real challenge for" or "a tangible obstacle for".
Exact(1)
The opposition of doctors most closely involved in the care of the dying to a change in the law may pose a practical difficulty for implementing any new legislation, since under the terms of the Bill, those likely to be most involved in the process of assessment prior to assisted suicide are more opposed to a change in the law.
Similar(59)
A practical difficulty arises, since no exact mathematical solution is possible for all except the simplest of mechanisms.
However, a practical difficulty prevents the obvious straightforward comparison between all genomes, looking for genes which would be ubiquitous.
However, this causes a practical difficulty in modelling such systems.
Despite these advances, cell mechanical integrity has always been an issue, as the long, high-aspect-ratio micro-tubes are extremely fragile against application of a longitudinal force, which results in practical difficulties for single-cell handling and stack assembly.
The rationalisation of guidelines across the health-board was again justified by the fact that the absence of a coherent framework was leading to practical difficulties for patients and the MDT alike.
The letter – part of the government's cross-departmental planning for a no-deal Brexit – shows the concern about practical difficulties for key public services from border delays and increased trade friction in the event of no deal.
In the medical image community, the idea to indicate IHD or infarction accurately via quantification of myocardial kinematic function has stimulated a huge number of computing algorithms to overcome practical difficulties, for example, relatively sparse spatial resolution and low temporal sampling rate of current imaging modalities.
Acute pain in the pre-operative phase and the inclusion of patients with impaired cognitive function creates practical difficulties for measuring the effectiveness of FIB in a traditional way using sensory and motor function assessments [12].
Several factors contribute to this, e.g. the lack of trained therapists, high costs of delivering the treatment, and the practical difficulties for patients of scheduling weekly visits at a clinic.
Considering the practical difficulties for the disposal of these two wastes, fry-drying presents a potentially convenient method for their combined elimination by incineration of the final fry-dried sludge.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com