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The phrase "a powerful refutation of" is correct and usable in written English.
It can be used when discussing a strong argument or evidence that disproves or contradicts a claim or assertion.
Example: "The scientist presented a powerful refutation of the previously accepted theory, demonstrating its flaws through extensive research."
Alternatives: "a compelling rebuttal of" or "a strong counterargument to".
Exact(4)
To me, Robinson is a powerful refutation of this idea.
His training is itself a powerful refutation of the two-cultures split; he holds degrees in computer science, electrical engineering, and art, and he encourages his students to range broadly among disciplines in their own work.
The True Dawn comprises a powerful refutation of Wahhabi pretensions and perversities.
He won over the House with a powerful refutation of Maurice's allegations.
Similar(56)
A sophistical refutation (a refutation of the sort a Sophist might make) depends on some fallacy that the questioner counts on the answerer not spotting.
Lyell's second volume is both an explication, and a refutation, of Lamarck's theory of transmutation.
In Just Married, Stephen Macedo, a professor of politics at Princeton University, provides a closely reasoned, powerful, and persuasive refutation of the contention that same-sex marriage endangers "the channeling" of heterosexual sex into committed partnerships that forge the most advantageous environment for the rearing of children.
To adherents of a certain storyline, the performance was as much an affront as the result, a refutation of faith.
I have now inserted a refutation of a recent flawed criticism of such replacement [ 170].
This provided neither a theoretical basis for belief nor a refutation of skeptical arguments.
The frenetic second section begins with a burst, but the third is a refutation of that anxiety.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com