Our findings demonstrate that doxazosin induces the apoptotic signalling potentially via the activation of TGF- β1 pathway with a potential involvement of NF- κB nuclear effectors.
These data suggest a potential involvement of GHB-/GABAB-receptors and progesterone in mood and prosocial behavior.
However, it must be emphasized that the view of a potential involvement of caspases in proliferation is largely based on indirect evidence and therefore remains highly speculative.
Our recent finding that the phosphorylation status of DEK is altered during death receptor-mediated apoptosis suggested a potential involvement of DEK in stress signaling.
Similarly, we identified distinct molecular subgroups of BRAF-mutant tumors, and multidimensional analyses highlighted a potential involvement of oncomiRs in less-differentiated subgroups.
Taken together these data indicate that a certain proportion of Doublecortin interacts with AP-1 and/or AP-2 in vivo and are consistent with a potential involvement of Doublecortin in protein sorting or vesicular trafficking.
In light of these observations, zinc may also contribute to calcium signals caused by mercury-containing compounds other than TMS, and a potential involvement of zinc release in the immunomodulatory effects of these substances should be considered.
Our observations, in conjunction with the chromosomal location of PRODH, suggest a potential involvement of this gene in the 22q11-associated psychiandic and behavioural phenotypes.
The high level of CD177 expression is also maintained in airspace neutrophils, suggesting a potential involvement of CD177 in neutrophil infiltration under infectious diseases.
Furthermore, a potential involvement of the most relevant metabolites in DF hypersensitivity reactions could be excluded.
A potential involvement of BAMBI in inflammation remains to be explored, but appears a reasonable possibility, given the roles of TGFβ and Wnt in inflammation.
