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They felt that management options, including monitoring approaches, do not change the significance of a potential interaction, for, in spite of overriding an alert the clinician might actually take relevant clinical or biochemical monitoring measures.
Similar(59)
Rather, existing evidence for a potential interaction of warfarin with sulfonylureas is based on pharmacokinetic theories related to displaced plasma protein binding and hepatic metabolism.
Therefore, DoCer was also excluded as a potential interaction candidate for membrane Hsp70 interactions.
This indicates that this position is a potential interaction partner for agonists.
Thus, WD 1 and 2 repeats may be a common binding site for OsRac1 and OsRap2.6 and may possibly act as a potential interaction site or bridge for the three proteins.
Because the molecular alteration might be associated with tamoxifen resistance, simply correcting for the assumed tamoxifen benefit without a correction for a potential interaction between treatment and molecular alteration could bias the analysis for prognostic potential.
We explored a potential interaction by FGF-23 for the association between ADMA and mortality in the full Cox regression model by adding the interaction term ADMA × FGF-23.
FANCD2 also possesses DNA binding activity itself (Joo et al., 2011), and it might be that the combination of this basal DNA binding and a potential interaction with UHRF1 allows for a stable retention of FANCD2 at the ICL.
While that does not mean that those hot spots overlap the AluY insertions themselves, we nonetheless checked for a potential interaction effect between hot spots and AluY insertions, since such an interaction could account for part of the AluY effect.
We first looked for a potential interaction between Klotho and FGF signalling, in C. elegans.
Likewise, for other TPs such as mAbs, there must be a clear mechanistic rationale for a potential interaction with an SMD; otherwise, no interaction study should be needed.
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