Sentence examples for a potent function of from inspiring English sources

Independent of the regulatory mechanisms, our data provide strong evidence for a potent function of the newly discovered AHR-NRF2-SLPI/SPRR2D/EPGN axin in the pathogenesis of MADISH.

miR-210 is recognized to have the potent function of angiogenesis, and in this study intra-articular injection of ds miR-210 could enhance the angiogenesis around the injured site of the meniscus.

Sasazawa et al (2009) suggested that BMA, a potent functional suppressor of Bcl-xL, functions not as a small molecule that can inactivate by recognising the surface pocket of Bcl-xL but rather as a modulator of cellular pH which induces the alternation between pro- and anti-apoptotic protein function.

The potent functions of FoxO1 are tightly controlled by its transcription and phosphorylation states.

Consistent with previous reports (Pesce et al., 2009), we found that compared to PECs isolated from PBS-injected WT mice, chitin-elicited PECs severely inhibited CD4+ T cell proliferation in response to OVA (Fig. 3A, filled gray histogram versus black line), demonstrating a potent suppressive function of chitin-polarized M2 macrophages.

The present results are perfectly supported by our revolutionary findings obtained in the adjuvant arthritis rat model 10 years ago, when we described a potent protective function of capsaicin-sensitive afferents via somatostatin release (Helyes et al., 2004).

Thus, targeting of TrxR1 by APR-246 provides a potent gain-of-function effect in addition to inhibition of cellular TrxR1 activity.

In the present paper, we have identified a potent modulating role of PMap on monocyte functions.

In this study, we demonstrated that nobiletin is a potent inhibitor of platelet function that acts through similar effects on platelet function, and established these mechanisms as common modes of action which flavonoids may share in order to modulate the function of these cells.

Of interest, cells in circulation experience hydrodynamic shear forces, which have been shown to be a potent regulator of cellular function in the vasculature and play an important role in maintaining tissue homeostasis.

Ginsenoside Rg3, present in steamed ginseng (Panax Ginseng C.A. Meyer), is thought to be a potent modulator of vascular function.