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These findings raise the possibility that thalidomide has a potent effect on the immune system or may even kill myeloma cells directly.
It is possible, meanwhile, that a sustained decrease in calories coupled with a sustained increase in exercise might have a potent effect on aging (at the moment there are no large-scale studies under way, Fontana told me).
These remarkable events have a potent effect on the family's mature and thoughtful eldest daughter, Gelsomina Maria Alexandra Lunguu), accelerating her entry into womanhood; the "wonders" of the title could mean those natural unheralded wonders of nature that occur when children start to become grownups independent of their mum and dad.
In the marine aquatic system, the contaminants of sea water have a potent effect on survivability and reproductive efficiency of the animals (Rand, Wells, & Mcarty, 1995, His, Beiras, & Seaman, 1999).
Ad.RGD-IL-24 had a potent effect on the up-regulation of the expression of GRP78/Bip, GADD34 and Bax, down-regulation of the expression of Bcl-2 and Mcl-1, and induced the activation of Caspase-3, which may be responsible for its apoptosis-inducing effect on THP-1 cells.
Among the synthetic β-GalCer analogues (6a 6e) described herein, compound 6e exhibited a potent effect on the activation of β-GlcCer'ase function in vitro and reduced the transepidermal water loss (TEWL) level in a UVB-induced barrier disrupted mice model.
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Moreover, SC-59, a sorafenib derivative, had a more potent effect on cancer cell viability than sorafenib.
Hotchkiss et al. have shown that a Tat-BH4 conjugate had a high potent effect on decreasing sepsis-induced lymphocyte apoptosis in vivo in the mouse CLP model.
But when it comes to reading and understanding news stories online — like this one, for example — the medium can have a surprisingly potent effect on the message.
Antimycin A, however, caused a 70% reduction in mitochondrial membrane potential in STAT3-CKO cells and had a more potent effect on ATP level and mitochondrial ROS generation relative to rotenone.
A similar effect was observed for chondrocyte MMP-13 production with a less potent effect on RASF MMP-13 production.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com