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The phrase "a possible negative effect" is correct and usable in written English.
It can be used when discussing potential adverse outcomes or consequences of a particular action, decision, or situation.
Example: "The new policy may have a possible negative effect on employee morale if not implemented carefully."
Alternatives: "a potential adverse impact" or "a likely detrimental outcome."
Exact(20)
"For the typical gun control law," Professor Volokh said, "you'll have very little positive effect but a possible negative effect".
A possible negative effect of pain-relieving analgesics used during oocyte retrieval on fertilization and embryo development has been discussed.
Since its introduction for this purpose (Hartigan 1963), considerable concerns have been aroused about a possible negative effect of lithium on kidney function.
We assumed a possible negative effect of being tired based on previously published articles [16, 17]; however, both day and night shifts scored approximately the same (15.9 vs 16.1).
At first, Obama had reservations about her husband's presidential campaign, due to fears about a possible negative effect on their daughters.
A possible negative effect could be to demoralize research scientists as they come to know that what they are researching may already be known to another civilization.
Similar(40)
In this way, we avoided any possible negative effect of the water.
In order to augment the test database and emphasize possible negative effect of a composite slab on seismic performance, full-scale cyclic seismic testing was also conducted for three welded steel moment connections.
A breach of confidentiality can be demoralising with possible negative effect on the success of the client in reducing their drug use.
A large-scale multicenter RCT is needed to evaluate the possible negative effect of older RBCs in critically ill patients.
It has raised criticism on all fronts - from the fact that Whiteread is neither Jewish nor Austrian, to its possible negative effect on local trade and complaints about the loss of parking spaces for the square's residents.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com