The phrase "a possible defect of" is correct and usable in written English.
It can be used when discussing potential flaws or issues related to a specific subject or object.
Example: "The engineers are investigating a possible defect of the new software that could affect its performance."
Alternatives: "a potential flaw in" or "a possible issue with".
Interestingly, Sirt6-deficient animals develop profound lymphopenia as a result of a cell non-autonomous mechanism, suggesting a possible defect of relevant cytokines or growth factors involved in T cell function [31].
We investigated a possible defect of the migratory GABAergic precursors.
Abnormal T cell activation is observed in SpA, suggesting a possible defect of lymphocyte inhibitory molecules.
The objective of the study was to determine any possible defect of the immune system in such patients.
It is believed that a possible defect in regulation of biological functions is present in SSc fibroblasts.
Because HRR occurs predominantly, if not exclusively, in late S and G2 [ 39, 40], these cell cycle perturbations as well as decreased radiosurvival suggest a possible defect in HRR of spontaneous and radiation-induced DSBs in cells expressing the K1702M mutant.
H&E staining of TEBs of 8-week-old CYT-1 mice also suggested a possible defect in the architecture of CYT-1 TEBs, as suggested by an apparent decrease in body cell number and larger luminal spaces compared with controls.
The absence of this response in FAP patients would seem to suggest a possible defect in the role of PARP in radiation-induced DNA repair in this cancer-prone disease.
We noticed that in embryos cultured with the 70 kDa fragment, somites have unusually large somitocoels, suggesting a possible defect in the recruitment of core cells into the epithelium.
This kitten is thought to have a primary hereditary pulmonary alveolar proteinosis with a possible defect in the signalling pathway of the receptor of the granulocyte-macrophage colony-stimulating factor.
Recent data demonstrating an association of variants of KLK1 and KLK3 with lupus nephritis suggest a possible defect in the protective function of kallikreins in some lupus patients [ 17].
