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A possible complicating factor is saturation of the cVEMP, which is known to be an inhibitory reflex (Colebatch and Rothwell, 2004).
The authors should discuss the reason for the short lifespan, comparing it to their previous publications, and should also emphasize/discuss the mixed strain background as a possible complicating factor in the analysis of these mice.
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Another possible complicating factor is the fact that our mouse model produced severe OA by 56 days post-injury.
To our knowledge, no information is available comparing the synovial fluid and plasma glucose concentrations in diabetic patients, and, despite many possible complicating factors, DM-related variations in glycemia are likely to cause similar changes in the synovial fluid glucose concentration, and thus affect glucose delivery to the articular cartilage.
To those involved, it was not sure whether this was a temporary phenomenon that could be overcome with trust among the partners or that it would be a lasting complicating factor with possible destructive effects on the schoolBeat-alliance.
This complexity of the antioxidant defense system is definitely a complicating factor because the possible effect of a single antioxidant in isolation may differ from that in combination with other antioxidants.
Depression was raised as a complicating factor after stroke and a potential barrier to optimal care.
A new complicating factor is the Orams case.
The interior, domestic drama of Claire's troubled personal history is a brilliant complicating factor.
A second complicating factor is that Polanski's work is filled with beauty and humanity.
Protein receptor rearrangements upon ligand binding are a major complicating factor in structure-based drug design.
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