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We are glad to report that applying the proposed guidelines, our validation process achieved very reasonable scores, achieving a positive ranking in four and an intermediate ranking in one, of five applicable items.
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These three measures yield a positive rank of motifs, i.e., their score is proportional to the rank.
It is interesting to ask whether there are any commonalities among the 22 "counterexample" species in which we observed a positive rank correlation between 5′-energy and ORF length.
(Note that although a positive rank correlation coefficient for the latter complex is reported in Table 5, at a lower oxygen fugacity (log = -77.5) an inverse correlation results between experimental abundances and calculated metastable equilibrium relative abundances of the proteins in this complex; see Additional File 6).
To answer this question, we examined the phylogenetic relationship of all the studied species and the distribution along this phylogeny of those 22 species exhibiting a positive rank correlation between ORF length and 5′ free energy (supplementary fig. S1, Supplementary Material online).
A negative Δ Rank value means, in the extended similarity the compound is ranked lower, a positive Δ Rank that it is ranked higher than by the docking procedure.
A negative Δ Rank value means, in the MCS similarity the compound is ranked lower, a positive Δ Rank that it is ranked higher than by the docking procedure.
This indicated a strong positive rank-correlation of expression between the normalized and non-normalized libraries.
Ironically, Date Night earned a somewhat decent 66% on Rotten Tomatoes (his first overall positive ranking), even if many of those positives where of the B-, 'st's not that good, but we love watching Carell and Fey do their shtick' variety.
The SM maps associated with the positive ranking scores are listed to the end user in decreasing order.
A statistically significant positive rank correlation of 0.6 was observed between circulating IL-6 levels and Sap.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com