The phrase "a positive amplification loop" is correct and usable in written English.
It can be used in contexts discussing feedback mechanisms, systems theory, or processes that enhance or reinforce positive outcomes.
Example: "In our marketing strategy, we aim to create a positive amplification loop that encourages customer engagement and loyalty."
Alternatives: "a beneficial feedback loop" or "a constructive reinforcement cycle".
We show that following mechanical ventilation, IL-1β bioactivation is not caspase-1 dependent but appears to be mediated by neutrophil factors, leading to a positive amplification loop and further propagation of the inflammatory response.
Moreover, IFNI, in turn, induce TLR3 expression in a positive amplification loop.
Activated caspase-3 then cleaved XIAP for proteasomal degradation, thereby initiating a positive amplification loop causing enhanced apoptosis.
As miR-155 is a TNFα-inducible transcript, these findings taken together suggest the possibility of a positive amplification loop.
The observations that p38 is required for maximal levels of Smad2 phosphorylation and for proper Nodal/activin target gene expression, together with the finding that p38 acts downstream of Nodal/activin, argue that p38 acts in a positive amplification loop for Nodal signaling.
Caspase-9 and-3 could reinforce Puma activation and apoptosis through two positive amplification loops.
Downstream caspase-3 reinforces Bak activation and the release of AIF and endoG through positive amplification loops.
Cathepsins also cleave and activate caspase-1 [76], and both cathepsins and caspase-1 cleave Bid [30], [60], [62], [63], further augmenting a positive feedback amplification loop.
Cell death and ROS induce ET synthesis, which feeds into a positive forward amplification loop enhancing ROS production [ 39].
As PUMA expression was regulated by p53, the PUMA, Bcl-XL and p53 in rotenone-treated cells form a positive feedback amplification loop to increase the apoptosis sensitivity.
Both elevated endogenous SA and application of exogenous SA in Arabidopsis and tobacco are accompanied by increased ROS (H2O2 and O2-) production [ 33- 36], indicating the existence of a positive feedback amplification loop with SA and ROS as central players.
