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The advantage of inferring recombination from LD is that it integrates the many recombination events occurring in the history of a population, instead of the rather few that occur in the generation of a mapping population.
The observation that non-recombining blocks present low-divergence between species in opposition to the whole gene, suggests the occurrence of migration followed by recombination, where new haplotypes are created by recombining different alleles inside a population instead of by the occurrence of new mutations.
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Conversely, provided that the organism studied has a relatively small genome size, whole sequencing of a subset of individuals derived from a mapping population, instead of a single inbred individual, could provide sufficient data for the de novo assembly of the organism's genome and for the positioning of sequence contigs derived from the sequence assembly into a genetic map.
'Avoidable' deaths are then the component of excess (cancer-related) mortality that would not occur if relative survival were at the higher level seen in a comparator population, instead of what was actually observed.
If we assumed accuracies of g PB and g CB were equal, the index accuracy increased from 0.49 to 0.60 (23% increase) with a CB versus a PB reference population, instead of an increase from 0.49 to 0.55 (13% increase; Figure 1).
Also, 100% of the patients in the phase 3 studies and 78% of the patients in the phase 2b trial met criteria for IBS‐D, so these data may be more applicable to an IBS‐D population instead of the non‐C IBS population.
It is also useful for EvoCK to start from a knowledge-rich population instead of a random one.
21 By using a before and after design, we could 'control' the impact of PS-HEMS with a recent historic population, instead of performing a traditional ground vs. air study.
These interventions are ineffective – or worse – because they treat "the obese" as an abstract, pathological population instead of a group of actual people who are part of the social fabric.
Evolutionary modelling approaches led to the proposal of a new therapeutic strategy that aims to maintain a stable tumour population instead of trying to achieve maximal cell kill (Gatenby et al, 2009).
TLR4 Thr399Ile polymorphism has been established as a genetic risk for gastritis and precancerous lesions in a north Indian population instead of Asp299Gly polymorphism by Achyut et al. [ 35].
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