However, co-expression of high levels of p16/p14ARF mRNA predicted a poor event-free survival (P=0.046, log-rank test).
However, high levels of p16/p14ARF mRNA expression were predictive of a poor event-free survival and should be investigated further.
Seven-time champion Stephen Hendry believes the World Championship would be a "poorer event" without Ronnie O'Sullivan.
Meanwhile, Australia all-rounder Shane Watson believes the World Twenty20 tournament in Bangladesh, which is now under way, is a poorer event without Pietersen.
Specifically, samples overexpressing this module had significantly better clinical outcomes, as measured by absence of a poor outcome event (disease-specific death or the surrogate distant metastasis if the former was unavailable).
Specifically, samples classified as good prognosis with overexpression of the immune response-module ('good-up' group) have less than half the risk of a poor outcome event (death or distant metastasis) relative to samples classified as poor prognosis, a result that we found to be independent of LN status and chemotherapy (Table 4).
In univariate analysis, 11q deletion, 17q gain and a segmental genomic type were associated with a poorer event-free survival (EFS) (P<0.0001, P=0.0002 and P<0.0001, respectively).
A few previous studies have shown a negative impact of comorbidity on CML survival in line with our results, mainly reflected in a poorer event-free survival [ 36] or lower degree of complete cytogenic response [ 41, 42].
Secondly, Mallidi et al 2004, has shown that patients with uncorrected mild to moderate IMR at the time of CABG had a poorer event-free survival, worse late functional status and worsening in the degree of mitral regurgitation [ 10].
Their findings suggest that chronic inflammation and activated coagulation associated with HIV lead to a poor outcome when CVD event occurs.
