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Sensitivity analyses were conducted to determine whether base case cost-effectiveness estimates (i.e. ICERs) would change substantially given a plausible level of variation in costs and outcomes.
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But Cas and Salford have at least secured planning permission, and come up with a reasonably plausible level of detail.
We show that two mechanisms, in addition to the lengthening of pathway, can lower the Hill coefficient to a biologically plausible level required for sustained oscillations.
We envision that the inclusion of more regulatory interactions may further decrease the sensitivity of the depletion time with respect to parameter variations to a physiologically plausible level.
Indeed, both EMu and NMF often attribute at least a small number of mutations to every available signature, which for many exposures does not correspond to a biologically plausible level of exposure.
Secondly, claims against currently living people are unreasonable if in fulfilling them the currently living people will bring about minimal or even trivial improvements of the well-being of future people but suffer losses themselves, causing them to fall below a plausible threshold level of well-being.
Furthermore, with the technical trend pointing to more selling pressure to come for the FTSE 100, 6380 looks like the next plausible level for some meaningful support.
There is no plausible level of spending cuts to offset the damage; the result would be chronic deficits and debilitating debt.
Error potential severity, based on the plausible level of patient injury, was classified using the Healthcare Failure Mode and Effect Analysis HFMEAA) Severity Rating Scale [ 15] (Table 2).
These correspond to a drug target that is cell-intrinsic and not shared (T = 0) and to two biologically plausible levels of transferability in the molecule used as a drug target.
We found plausible levels of nutrient intakes and in line with expectations, a large proportion of subjects did not meet healthy diet recommendations.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com