Sentence examples for a pivotal trigger from inspiring English sources

However, recent investigations have revealed a critical role for the innate immune system as a pivotal trigger in adaptive immune responses.

The alterations of calcium (Ca) and phosphate (P) homeostasis in renal patients, mainly driven by a derangement of Klotho/fibroblast growth factor 23FGF2323)—parathormone (PTH vitamin D axis, are considered pivotal triggers and regulators of vascular ageing rather than mere biomarkers of CKD-MBD syndrome [ 3].

Obsession takes its time, but looking back, the pivotal triggers aren't usually hard to identify.

It turns out that a ubiquitous regulatory cell protein called transforming growth factor beta-1 (TGF-1) played a pivotal role in triggering the dental stem cells to grow into dentin.

These results indicate that signal transducer and activator of transcription 1 dephosphorylation, HO-1 and its upstream effector, Nrf2, play a pivotal role in triggering an anti-inflammatory signaling cascade of sulforaphane that results in decreases of IL-1β release and microRNA-146a production in Aβ1 42-stimulated humAβ1 42-stimulated cells.

And the sun seems to have played a pivotal role in triggering droughts and cold snaps.

These findings highlight how surface nanotopography may play a pivotal role in triggering and guiding specific biological outcomes.

In addition, the changes observed in IL-6 expression profile suggest that this pro-inflammatory cytokine plays a pivotal role in triggering the healing cascade.

Thus, it has been suggested that those released proinflammatory cytokines, but especially IFN-γ, possess a pivotal role in triggering cellular changes that contribute to gastric mucosal damage [38], [39].

ROS play a pivotal role as triggers of gene expression during biotic and abiotic stresses [ 49].

The tumor suppressor p53 plays a pivotal role in triggering senescence and apoptosis and suppressing tumorigenesis.