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The phrase "a pivotal difference between" is correct and usable in written English.
It can be used when discussing significant distinctions or contrasts between two or more subjects or concepts.
Example: "There is a pivotal difference between traditional education and online learning in terms of accessibility and flexibility."
Alternatives: "a crucial distinction between" or "a significant difference between".
Exact(1)
Preference to the two major receptor types, α2,3- and α2,6-linked sialic acid, is a pivotal difference between avian and human influenza viruses [2].
Similar(59)
Your assistance can similarly make a pivotal difference for not just Prey Lang, but entire ecosystems and communities fighting against deforestation and greed-driven injustices worldwide.
The pivotal difference between the two New Zealanders is this.
Of all variables, the age at marriage may be the pivotal difference between red and blue families.
However, the pivotal difference between the OBO Relation Ontology and UML lies in the fact that instance-level relations are formally defined in the former, i.e., they form a set of primitive relations, whereas links are not formally defined in the latter.
Will Harrel Houston, Dec. 6, 2008 To the Editor: As someone who lived through the Vietnam War and saw friends and family shipped overseas, it strikes me that one of the pivotal differences between then and now is the lack of a military draft.
But super fans of the book may notice some pivotal differences between the novel and the screen version of the beloved story.
46 Hence, all these investigations show limited evidence of pivotal differences between various drug classes; treatment success is dependent on which collateral outcome is preferred.
But there is one pivotal difference this year.
Gaddafi's future has become a pivotal issue between the regime and the opposition, which has demanded his departure.
Thereby, the similarity of chemical properties of different metals plays a pivotal role especially between essential and non-essential metals.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com