The phrase "a physiological requirement" is correct and usable in written English.
It can be used when discussing the necessary biological or physical needs of an organism or system.
Example: "Water is a physiological requirement for all living organisms to maintain homeostasis."
Alternatives: "a biological necessity" or "a physical need".
Demonstrating a physiological requirement for autocrine prolactin, mammary glands from lactation-defective Akt1 Akt2 mice failed to express autocrine prolactin or activate Stat5 during late pregnancy despite normal levels of circulating serum prolactin and pituitary prolactin production.
These studies establish a physiological requirement for ankyrins in localization of a variety of ion channels in excitable membranes in the heart and nervous system, and suggest a new class of functional channelopathies due to abnormal cellular localization.
These data provide the first evidence of a physiological requirement for ankyrin-B in intracellular targeting of the calcium homeostasis machinery of striated muscle and immune system, and moreover, support a catalytic role that does not involve permanent stoichiometric complexes between ankyrin-B and targeted proteins.
It is known that the Myc-α-tubulin interaction is disrupted during mitosis by a specific phosphorylation of Myc at Thr-58, suggesting that the loss of such interaction at mitosis may be a physiological requirement for cell division [52].
These in vivo results indicate a physiological requirement for this domain [28] and leads us to predict that HDAC4ΔC mice would show hypersensitized responses in a chronic cocaine administration model.
However, we were unable to demonstrate a physiological requirement for the ManD (Uniprot entry Q1QT89; CsManD) that catalyzes the dehydration of d-mannonate (kcat/ KM = 5 M–1 s–1) and d-gluconate (kcat/ KM = 40 M–1 s–1).
The maintenance of ion homeostasis in plant cells is a fundamental physiological requirement for sustainable plant growth, development, and production.
Coupled with a reduction in mitochondrial DNA, these results suggest that maintenance of mitochondrial integrity, at either the DNA or protein level, is a key physiological requirement for mitochondrial fusion in the adult heart.
These studies suggest an important physiological requirement for ascorbate in conditions of stress and disease burden.
Several publications and reviews have discussed the quantification of the physiological requirement of vitamin E as a function of PUFA intake.
Sodium is an essential nutrient that regulates blood volume, blood pressure, osmotic equilibrium and pH; the minimum physiological requirement for sodium is 500 milligrams per day.
